Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

PURPOSE: Ductal prostate cancer (dPC) is a rare variant of prostatic adenocarcinoma associated with poor outcomes. Although its histopathologic features are well characterized, the underlying molecular hallmarks of this aggressive subtype are not well described. We sought to provide a comprehensive...

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Détails bibliographiques
Publié dans:JCO Precis Oncol
Auteurs principaux: Schweizer, Michael T., Antonarakis, Emmanuel S., Bismar, Tarek A., Guedes, Liana B., Cheng, Heather H., Tretiakova, Maria S., Vakar-Lopez, Funda, Klemfuss, Nola, Konnick, Eric Q., Mostaghel, Elahe A., Hsieh, Andrew C., Nelson, Peter S., Yu, Evan Y., Montgomery, R. Bruce, True, Lawrence D., Epstein, Jonathan I., Lotan, Tamara L., Pritchard, Colin C.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2019
Sujets:
Original Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528668/
https://ncbi.nlm.nih.gov/pubmed/31123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00327
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