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Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

PURPOSE: Ductal prostate cancer (dPC) is a rare variant of prostatic adenocarcinoma associated with poor outcomes. Although its histopathologic features are well characterized, the underlying molecular hallmarks of this aggressive subtype are not well described. We sought to provide a comprehensive...

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Publicado en:JCO Precis Oncol
Autores principales: Schweizer, Michael T., Antonarakis, Emmanuel S., Bismar, Tarek A., Guedes, Liana B., Cheng, Heather H., Tretiakova, Maria S., Vakar-Lopez, Funda, Klemfuss, Nola, Konnick, Eric Q., Mostaghel, Elahe A., Hsieh, Andrew C., Nelson, Peter S., Yu, Evan Y., Montgomery, R. Bruce, True, Lawrence D., Epstein, Jonathan I., Lotan, Tamara L., Pritchard, Colin C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Clinical Oncology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528668/
https://ncbi.nlm.nih.gov/pubmed/31123724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00327
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