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APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice

Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglial interactions with amyloid plaques that exert impor...

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Podrobná bibliografie
Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Stephen, T. L., Cacciottolo, M., Balu, D., Morgan, T. E., LaDu, M. J., Finch, C. E., Pike, C. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528326/
https://ncbi.nlm.nih.gov/pubmed/31113487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0729-z
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