APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice

Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglial interactions with amyloid plaques that exert impor...

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Bibliographic Details
Published in:Acta Neuropathol Commun
Main Authors: Stephen, T. L., Cacciottolo, M., Balu, D., Morgan, T. E., LaDu, M. J., Finch, C. E., Pike, C. J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528326/
https://ncbi.nlm.nih.gov/pubmed/31113487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0729-z
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