The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer’s Disease of humans and mice

The APOE4 allele confers greater risk of Alzheimer’s Disease (AD) for women than men, in conjunction with greater clinical deficits per unit of AD neuropathology (plaques, tangles). Cerebral microbleeds, which contribute to cognitive dysfunctions during AD, also show APOE4 excess, but sex-APOE allel...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Cacciottolo, Mafalda, Christensen, Amy, Moser, Alexandra, Liu, Jiahui, Pike, Christian J., Sullivan, Patrick M., Morgan, Todd E., Dolzhenko, Egor, Charidimou, Andreas, Wahlund, Lars-Olaf, Wiberg, Maria Kristofferson, Shams, Sara, Chiang, Gloria Chia-Yi, Finch, Caleb E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687024/
https://ncbi.nlm.nih.gov/pubmed/26686669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.10.010
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars