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Age, sex, and cerebral microbleeds in EFAD Alzheimer Disease mice

Cerebral microbleeds (MBs) increase at later ages in association with increased cognitive decline and Alzheimer Disease (AD). MB prevalence is also increased by APOE4 and hypertension. In EFAD mice (5XFAD(+/−)/human APOE(+/+)), cerebral cortex MBs are most prevalent in E4 females at 6 mo, parallelin...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Cacciottolo, Mafalda, Morgan, Todd E, Finch, Caleb E
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178216/
https://ncbi.nlm.nih.gov/pubmed/33813349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2021.02.020
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