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Control of mRNA Splicing by Intragenic RNA Activators of Stress Signaling: Potential Implications for Human Disease
A critical step in the cellular stress response is transient activation of the RNA-dependent protein kinase PKR by double-helical RNA, resulting in down-regulation of protein synthesis through phosphorylation of the α chain of translation initiation factor eIF2, a major PKR substrate. However, intra...
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| Опубликовано в: : | Front Genet |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527590/ https://ncbi.nlm.nih.gov/pubmed/31139209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00464 |
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