Control of mRNA Splicing by Intragenic RNA Activators of Stress Signaling: Potential Implications for Human Disease

A critical step in the cellular stress response is transient activation of the RNA-dependent protein kinase PKR by double-helical RNA, resulting in down-regulation of protein synthesis through phosphorylation of the α chain of translation initiation factor eIF2, a major PKR substrate. However, intra...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Kaempfer, Raymond, Ilan, Lena, Cohen-Chalamish, Smadar, Turgeman, Orli, Namer, Lise Sarah, Osman, Farhat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527590/
https://ncbi.nlm.nih.gov/pubmed/31139209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00464
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