A cis-acting element in the 3′-untranslated region of human TNF-α mRNA renders splicing dependent on the activation of protein kinase PKR

We report a role for the 3′-untranslated region in control of mRNA splicing and show that human TNF-α 3′ UTR harbors a cis-acting element that renders splicing of precursor transcripts dependent on activation of PKR, the RNA-activated protein kinase that phosphorylates eukaryotic initiation factor 2...

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Detaylı Bibliyografya
Asıl Yazarlar: Osman, Farhat, Jarrous, Nayef, Ben-Asouli, Yitzhak, Kaempfer, Raymond
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 1999
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC317206/
https://ncbi.nlm.nih.gov/pubmed/10617576
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