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RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR

Besides TopBP1, ETAA1 has been identified more recently as an activator of the ATR-ATRIP complex in human cells. We have examined the role of ETAA1 in the Xenopus egg-extract system, which has been instrumental in the study of ATR-ATRIP. Depletion of ETAA1 from egg extracts did not noticeably reduce...

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Vydáno v:Cell Cycle
Hlavní autoři: Lyu, Ke, Kumagai, Akiko, Dunphy, William G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527274/
https://ncbi.nlm.nih.gov/pubmed/30975033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1598728
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