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RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

The Replication Protein A (RPA) complex is an essential regulator of eukaryotic DNA metabolism. RPA avidly binds to single-stranded DNA (ssDNA) through multiple oligonucleotide/oligosaccharide-binding folds and coordinates the recruitment and exchange of genome maintenance factors to regulate DNA re...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Maréchal, Alexandre, Zou, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650586/
https://ncbi.nlm.nih.gov/pubmed/25403473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.147
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