Loading...

Non-canonical ubiquitination of the cholesterol-regulated degron of squalene monooxygenase

Squalene monooxygenase (SM) is a rate-limiting enzyme in cholesterol synthesis. The region comprising the first 100 amino acids, termed SM N100, represents the shortest cholesterol-responsive degron and enables SM to sense excess cholesterol in the endoplasmic reticulum (ER) membrane. Cholesterol ac...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Chua, Ngee Kiat, Hart-Smith, Gene, Brown, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527178/
https://ncbi.nlm.nih.gov/pubmed/30940729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007798
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!