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Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy

The Parkinson disease‐associated proteins PINK1 and PRKN coordinate the ubiquitination of mitochondrial outer membrane proteins to tag them either for degradation or for autophagic clearance of the mitochondrion. The proteins include the mitochondrial trafficking proteins RHOT1 and RHOT2, the remova...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Safiulina, Dzhamilja, Kuum, Malle, Choubey, Vinay, Hickey, Miriam A., Kaasik, Allen
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526870/
https://ncbi.nlm.nih.gov/pubmed/30806158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1586260
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