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Negative-feedback coordination between proteasomal activity and autophagic flux

In eukaryotes, most proteins are degraded through one of the 2 major proteolytic pathways: the ubiquitin-proteasome system (UPS) and macroautophagy/autophagy. Existing evidence suggests that these processes are critical to human physiology and pathology. Our study revealed a negative feedback system...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Lee, Jung Hoon, Park, Seoyoung, Kim, Eunkyoung, Lee, Min Jae
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6526830/
https://ncbi.nlm.nih.gov/pubmed/30689498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1569917
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