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Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

BACKGROUND: In osteoarthritis (OA), cartilage matrix is lost despite vigorous chondrocyte anabolism. In this study, we attempted to determine whether altered matrix synthesis is involved in this paradox in disease progression through gene expression analysis and ultrastructural analysis of collagen...

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Vydáno v:BMC Musculoskelet Disord
Hlavní autoři: Tanaka, Nobuho, Tashiro, Toshiyuki, Katsuragawa, Yozo, Sawabe, Motoji, Furukawa, Hiroshi, Fukui, Naoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525975/
https://ncbi.nlm.nih.gov/pubmed/31103042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2596-y
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