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Expression of minor cartilage collagens and small leucine rich proteoglycans may be relatively reduced in osteoarthritic cartilage

BACKGROUND: In osteoarthritis (OA), cartilage matrix is lost despite vigorous chondrocyte anabolism. In this study, we attempted to determine whether altered matrix synthesis is involved in this paradox in disease progression through gene expression analysis and ultrastructural analysis of collagen...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Tanaka, Nobuho, Tashiro, Toshiyuki, Katsuragawa, Yozo, Sawabe, Motoji, Furukawa, Hiroshi, Fukui, Naoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525975/
https://ncbi.nlm.nih.gov/pubmed/31103042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2596-y
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