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Targeting RIPK1 for the treatment of human diseases

RIPK1 kinase has emerged as a promising therapeutic target for the treatment of a wide range of human neurodegenerative, autoimmune, and inflammatory diseases. This was supported by extensive studies which demonstrated that RIPK1 is a key mediator of apoptotic and necrotic cell death as well as infl...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Degterev, Alexei, Ofengeim, Dimitry, Yuan, Junying
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525537/
https://ncbi.nlm.nih.gov/pubmed/31048504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901179116
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