Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor

The transcription factor nuclear factor of activated T cells (NFAT) has a key role in both T cell activation and tolerance and has emerged as an important target of immune modulation. NFAT directs the effector arm of the immune response in the presence of activator protein-1 (AP-1), and T cell anerg...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Mognol, Giuliana P., González-Avalos, Edahí, Ghosh, Srimoyee, Spreafico, Roberto, Gudlur, Aparna, Rao, Anjana, Damoiseaux, Robert, Hogan, Patrick G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525529/
https://ncbi.nlm.nih.gov/pubmed/31019078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820604116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker