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Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis

Cell surface β-Amyloid precursor protein (APP) is known to have a functional role in iron homeostasis through stabilising the iron export protein ferroportin (FPN). Mechanistic evidence of this role has previously only been provided through transcriptional or translational depletion of total APP lev...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Tsatsanis, Andrew, Dickens, Stuart, Kwok, Jessica C. F., Wong, Bruce X., Duce, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525264/
https://ncbi.nlm.nih.gov/pubmed/30796750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-019-02747-y
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