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Refactoring the cryptic streptophenazine biosynthetic gene cluster unites phenazine, polyketide, and nonribosomal peptide biochemistry

The disconnect between the genomic prediction of secondary metabolite biosynthetic potential and the observed laboratory production profile of microorganisms is well-documented. While heterologous expression of biosynthetic gene clusters (BGCs) is often seen as a potential solution to bridge this ga...

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Bibliografische gegevens
Gepubliceerd in:Cell Chem Biol
Hoofdauteurs: Bauman, Katherine D., Li, Jie, Murata, Kazuya, Mantovani, Simone M., Dahesh, Samira, Nizet, Victor, Luhavaya, Hanna, Moore, Bradley S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525064/
https://ncbi.nlm.nih.gov/pubmed/30853419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.02.004
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