Inhibition of the hexosamine biosynthesis pathway potentiates cisplatin cytotoxicity by decreasing BiP expression in non-small cell lung cancer cells

Platinum anticancer agents are essential components in chemotherapeutic regimens for non-small cell lung cancer (NSCLC) patients ineligible for targeted therapy. However, platinum-based regimens have reached a plateau of therapeutic efficacy; therefore, it is critical to implement novel approaches f...

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Publicado no:Mol Carcinog
Main Authors: Chen, Wenshu, Chinh Do, Kieu, Saxton, Bryanna, Leng, Shuguang, Filipczak, Piotr, Tessema, Mathewos, Belinsky, Steven A., Lin, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525013/
https://ncbi.nlm.nih.gov/pubmed/30790354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22992
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