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Inhibition of the hexosamine biosynthesis pathway potentiates cisplatin cytotoxicity by decreasing BiP expression in non-small cell lung cancer cells

Platinum anticancer agents are essential components in chemotherapeutic regimens for non-small cell lung cancer (NSCLC) patients ineligible for targeted therapy. However, platinum-based regimens have reached a plateau of therapeutic efficacy; therefore, it is critical to implement novel approaches f...

詳細記述

保存先:
書誌詳細
出版年:Mol Carcinog
主要な著者: Chen, Wenshu, Chinh Do, Kieu, Saxton, Bryanna, Leng, Shuguang, Filipczak, Piotr, Tessema, Mathewos, Belinsky, Steven A., Lin, Yong
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525013/
https://ncbi.nlm.nih.gov/pubmed/30790354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22992
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