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Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans

Reduced protein homeostasis leading to increased protein instability is a common molecular feature of aging, but it remains unclear whether this is a cause or consequence of the aging process. In neurodegenerative diseases and other amyloidoses, specific proteins self-assemble into amyloid fibrils a...

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Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Huang, Chaolie, Wagner-Valladolid, Sara, Stephens, Amberley D, Jung, Raimund, Poudel, Chetan, Sinnige, Tessa, Lechler, Marie C, Schlörit, Nicole, Lu, Meng, Laine, Romain F, Michel, Claire H, Vendruscolo, Michele, Kaminski, Clemens F, Kaminski Schierle, Gabriele S, David, Della C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524967/
https://ncbi.nlm.nih.gov/pubmed/31050339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43059
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