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RNA Polymerase II promoter-proximal pausing in mammalian long non-coding genes

Mammalian genomes encode a large number of non-coding RNAs (ncRNAs) that greatly exceed mRNA genes. While the physiological and pathological roles of ncRNAs have been increasingly understood, the mechanisms of regulation of ncRNA expression are less clear. Here, our genomic study has shown that a si...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genomics
Auteurs principaux: Bunch, Heeyoun, Lawney, Brian P, Burkholder, Adam, Ma, Duanduan, Zheng, Xiaofeng, Motola, Shmulik, Fargo, David C, Levine, Stuart S, Wang, Yaoyu E, Hu, Guang
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524647/
https://ncbi.nlm.nih.gov/pubmed/27432546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2016.07.003
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