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Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals

Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis. Despite the prevalence of paused Pol II, very little is known about the dynamics of these e...

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Detalhes bibliográficos
Main Authors: Henriques, Telmo, Gilchrist, Daniel A., Nechaev, Sergei, Bern, Michael, Muse, Ginger W., Burkholder, Adam, Fargo, David C., Adelman, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845087/
https://ncbi.nlm.nih.gov/pubmed/24184211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.001
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