Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals

Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis. Despite the prevalence of paused Pol II, very little is known about the dynamics of these e...

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Hauptverfasser: Henriques, Telmo, Gilchrist, Daniel A., Nechaev, Sergei, Bern, Michael, Muse, Ginger W., Burkholder, Adam, Fargo, David C., Adelman, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845087/
https://ncbi.nlm.nih.gov/pubmed/24184211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.001
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