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Upstream Anti-sense Promoters are Hubs of Transcription Factor Binding and Active Histone Modifications

Anti-sense transcription originating upstream of mammalian protein-coding genes is a well-documented phenomenon, but remarkably little is known about the regulation or function of anti-sense promoters and the non-coding RNAs they generate. Here we define at nucleotide resolution the divergent transc...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell
Hauptverfasser: Scruggs, Benjamin S., Gilchrist, Daniel A., Nechaev, Sergei, Muse, Ginger W., Burkholder, Adam, Fargo, David C., Adelman, Karen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475495/
https://ncbi.nlm.nih.gov/pubmed/26028540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.04.006
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