Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals

Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis. Despite the prevalence of paused Pol II, very little is known about the dynamics of these e...

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Main Authors: Henriques, Telmo, Gilchrist, Daniel A., Nechaev, Sergei, Bern, Michael, Muse, Ginger W., Burkholder, Adam, Fargo, David C., Adelman, Karen
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845087/
https://ncbi.nlm.nih.gov/pubmed/24184211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.001
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