Early neuronal accumulation of DNA double strand breaks in Alzheimer’s disease

The maintenance of genomic integrity is essential for normal cellular functions. However, it is difficult to maintain over a lifetime in postmitotic cells such as neurons, in which DNA damage increases with age and is exacerbated by multiple neurological disorders, including Alzheimer’s disease (AD)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Shanbhag, Niraj M., Evans, Mark D., Mao, Wenjie, Nana, Alissa L., Seeley, William W., Adame, Anthony, Rissman, Robert A., Masliah, Eliezer, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524256/
https://ncbi.nlm.nih.gov/pubmed/31101070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0723-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados