MDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and PDAC-derived xenografts grow as a result of altered metabolic pathways, changes in stroma, and autophagy. Selective targeting and inh...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: New, Maria, Van Acker, Tim, Sakamaki, Jun-ichi, Jiang, Ming, Saunders, Rebecca E., Long, Jaclyn, Wang, Victoria M.-Y., Behrens, Axel, Cerveira, Joana, Sudhakar, Padhmanand, Korcsmaros, Tamas, Jefferies, Harold B. J., Ryan, Kevin M., Howell, Michael, Tooze, Sharon A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522344/
https://ncbi.nlm.nih.gov/pubmed/30765601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2553
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky