MDH1 and MPP7 regulate autophagy in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is driven by metabolic changes in pancreatic cells caused by oncogenic mutations and dysregulation of p53. PDAC cell lines and PDAC-derived xenografts grow as a result of altered metabolic pathways, changes in stroma, and autophagy. Selective targeting and inh...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: New, Maria, Van Acker, Tim, Sakamaki, Jun-ichi, Jiang, Ming, Saunders, Rebecca E., Long, Jaclyn, Wang, Victoria M.-Y., Behrens, Axel, Cerveira, Joana, Sudhakar, Padhmanand, Korcsmaros, Tamas, Jefferies, Harold B. J., Ryan, Kevin M., Howell, Michael, Tooze, Sharon A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522344/
https://ncbi.nlm.nih.gov/pubmed/30765601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-2553
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items