A carregar...
Inhibition of γ-Glutamyl Transpeptidase or Cysteine S-Conjugate β-Lyase Activity Blocks the Nephrotoxicity of Cisplatin in Mice
Cisplatin is nephrotoxic. The mechanism underlying this organ-specific toxicity is unknown. We hypothesize that cisplatin is metabolized via a γ-glutamyl transpeptidase (GGT) and cysteine S-conjugate β-lyase-dependent pathway that has been shown to activate several haloalkenes to nephrotoxins. To te...
Na minha lista:
| Publicado no: | J Pharmacol Exp Ther |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6522257/ https://ncbi.nlm.nih.gov/pubmed/11752109 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|