Distinct roles of RZZ and Bub1-KNL1 in mitotic checkpoint signaling and kinetochore expansion

The Mad1-Mad2 heterodimer is the catalytic hub of the spindle assembly checkpoint (SAC), which controls M phase progression through a multi-subunit anaphase inhibitor, the mitotic checkpoint complex (MCC) [1, 2]. During interphase, Mad1-Mad2 generates MCC at nuclear pores [3]. After nuclear envelope...

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Publicado no:Curr Biol
Main Authors: Rodriguez-Rodriguez, Jose-Antonio, Lewis, Clare, McKinley, Kara L., Sikirzhytski, Vitali, Corona, Jennifer, Maciejowski, John, Khodjakov, Alexey, Cheeseman, Iain M., Jallepalli, Prasad V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522255/
https://ncbi.nlm.nih.gov/pubmed/30415700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.10.006
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