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Methamphetamine decreases k(+) channel function in human fetal astrocytes by activating the trace amine-associated receptor type-1

Methamphetamine (Meth) is a potent and commonly abused psychostimulant. Meth alters neuron and astrocyte activity; yet the underlying mechanism(s) is not fully understood. Here we assessed the impact of acute Meth on human fetal astrocytes (HFAs) using whole-cell patch-clamping. We found that HFAs d...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Dave, Sonya, Chen, Lihua, Yu, Chunjiang, Seaton, Melanie, Khodr, Christina E., Al-Harthi, Lena, Hu, Xiu-Ti
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522225/
https://ncbi.nlm.nih.gov/pubmed/30295919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14606
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