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Triumeq Increases Excitability of Pyramidal Neurons in the Medial Prefrontal Cortex by Facilitating Voltage-Gated Ca(2+) Channel Function

Combination antiretroviral therapy (cART) suppresses HIV-1 replication, improves immune function, and prolongs the life of people living with HIV (PLWH). However, cART also induces neurotoxicity that could complicate HIV-induced neurodegeneration while reduce its therapeutic efficacy in treating HIV...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Lihua, Al-Harthi, Lena, Hu, Xiu-Ti
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876243/
https://ncbi.nlm.nih.gov/pubmed/33584297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.617149
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