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Aging alters voltage-gated calcium channels in prefrontal cortex pyramidal neurons in the HIV brain

We assessed firing and voltage-gated Ca(2+) influx in medial prefrontal cortex (mPFC) pyramidal neurons from older (12 month-old) HIV-1 transgenic (Tg) rats. We found that neurons from older Tg rats showed increased firing compared to non-Tg rats, but Ca(2+) spikes were unchanged. However, stronger...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Khodr, Christina E., Chen, Lihua, Al-Harthi, Lena, Hu, Xiu-Ti
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492926/
https://ncbi.nlm.nih.gov/pubmed/29090376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-017-0588-y
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