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Combined chronic blockade of hyper-active L-type calcium channels and NMDA receptors ameliorates HIV-1 associated hyper-excitability of mPFC pyramidal neurons

Human Immunodeficiency Virus type 1 (HIV-1) infection induces neurological and neuropsychological deficits, which are associated with dysregulation of the medial prefrontal cortex (mPFC) and other vulnerable brain regions. We evaluated the impact of HIV infection in the mPFC and the therapeutic pote...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Khodr, Christina E., Chen, Lihua, Dave, Sonya, Al-Harthi, Lena, Hu, Xiu-Ti
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983475/
https://ncbi.nlm.nih.gov/pubmed/27326669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.06.008
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