Pharmacokinetic testing of a first generation cabotegravir prodrug in rhesus macaques

Long-acting antiretrovirals can improve therapy and prevention for HIV-1 infection. Current long-acting cabotegravir (CAB LAP) can be administered every other month. Previously, we demonstrated that a myristoylated CAB prodrug encased in poloxamer 407 provided extended plasma drug concentrations. We...

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Bibliografiska uppgifter
I publikationen:AIDS
Huvudupphovsmän: McMillan, JoEllyn, Szlachetka, Adam, Zhou, Tian, Morsey, Brenda, Lamberty, Benjamin, Callen, Shannon, Gautam, Nagsen, Alnouti, Yazen, Edagwa, Benson, Gendelman, Howard E., Fox, Howard S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521853/
https://ncbi.nlm.nih.gov/pubmed/30289818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002032
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