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HMGB1 inhibits insulin signaling through TLR4 and RAGE in human retinal endothelial cells

In the past decade, the role of inflammation has been shown in diabetes and its complications. Little is available on high mobility group box 1 (HMGB1) actions on the proteins involved in insulin signal transduction, which may be altered to result in insulin resistance in the retina. REC were grown...

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Vydáno v:Growth Factors
Hlavní autoři: Jiang, Youde, Steinle, Jena J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521723/
https://ncbi.nlm.nih.gov/pubmed/31084273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08977194.2018.1539393
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