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Noninvasive Imaging and Quantification of Radiotherapy-Induced PD-L1 Upregulation with (89)Zr–Df–Atezolizumab

Immune checkpoint expression is highly dynamic, and combination treatments including radiotherapy can particularly modulate this expression. PET imaging using (89)Zr–Df–atezolizumab can provide insight into the levels of PD-L1 variation following radiotherapy treatments. In vitro screening was used...

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Bibliografiske detaljer
Udgivet i:Bioconjug Chem
Main Authors: Ehlerding, Emily B., Lee, Hye Jin, Barnhart, Todd E., Jiang, Dawei, Kang, Lei, McNeel, Douglas G., Engle, Jonathan W., Cai, Weibo
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521689/
https://ncbi.nlm.nih.gov/pubmed/30973703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00178
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