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Noninvasive Imaging and Quantification of Radiotherapy-Induced PD-L1 Upregulation with (89)Zr–Df–Atezolizumab

Immune checkpoint expression is highly dynamic, and combination treatments including radiotherapy can particularly modulate this expression. PET imaging using (89)Zr–Df–atezolizumab can provide insight into the levels of PD-L1 variation following radiotherapy treatments. In vitro screening was used...

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Sonraí Bibleagrafaíochta
Foilsithe in:Bioconjug Chem
Main Authors: Ehlerding, Emily B., Lee, Hye Jin, Barnhart, Todd E., Jiang, Dawei, Kang, Lei, McNeel, Douglas G., Engle, Jonathan W., Cai, Weibo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521689/
https://ncbi.nlm.nih.gov/pubmed/30973703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00178
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