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(89)Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer
PURPOSE: Nivolumab is a human monoclonal antibody that is specific for programmed cell death-1 (PD-1), a negative regulator of T-cell activation and response. Acting as an immune checkpoint inhibitor, nivolumab binds to PD-1 expressed on the surface of many immune cells and prevents ligation by its...
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| Udgivet i: | Eur J Nucl Med Mol Imaging |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5700850/ https://ncbi.nlm.nih.gov/pubmed/28821924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-017-3803-4 |
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