(89)Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer

PURPOSE: Nivolumab is a human monoclonal antibody that is specific for programmed cell death-1 (PD-1), a negative regulator of T-cell activation and response. Acting as an immune checkpoint inhibitor, nivolumab binds to PD-1 expressed on the surface of many immune cells and prevents ligation by its...

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Vydáno v:Eur J Nucl Med Mol Imaging
Hlavní autoři: England, Christopher G., Jiang, Dawei, Ehlerding, Emily B., Rekoske, Brian T., Ellison, Paul A., Hernandez, Reinier, Barnhart, Todd E., McNeel, Douglas G., Huang, Peng, Cai, Weibo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700850/
https://ncbi.nlm.nih.gov/pubmed/28821924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-017-3803-4
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