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Estimating uncertainty in predicted folding free energy changes of RNA secondary structures

Nearest neighbor parameters for estimating the folding stability of RNA are commonly used in secondary structure prediction, for generating folding ensembles of structures, and for analyzing RNA function. Previously, we demonstrated that we could quantify the uncertainties in each nearest neighbor p...

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Publicat a:RNA
Autors principals: Zuber, Jeffrey, Mathews, David H.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521603/
https://ncbi.nlm.nih.gov/pubmed/30952689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069203.118
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