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Using an RNA secondary structure partition function to determine confidence in base pairs predicted by free energy minimization

A partition function calculation for RNA secondary structure is presented that uses a current set of nearest neighbor parameters for conformational free energy at 37°C, including coaxial stacking. For a diverse database of RNA sequences, base pairs in the predicted minimum free energy structure that...

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Detalhes bibliográficos
Autor principal: MATHEWS, DAVID H.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370608/
https://ncbi.nlm.nih.gov/pubmed/15272118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7650904
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