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Analysis of RNA nearest neighbor parameters reveals interdependencies and quantifies the uncertainty in RNA secondary structure prediction

RNA secondary structure prediction is often used to develop hypotheses about structure-function relationships for newly discovered RNA sequences, to identify unknown functional RNAs, and to design sequences. Secondary structure prediction methods typically use a thermodynamic model that estimates th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: Zuber, Jeffrey, Cabral, B. Joseph, McFadyen, Iain, Mauger, David M., Mathews, David H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191722/
https://ncbi.nlm.nih.gov/pubmed/30104207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.065102.117
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