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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir
Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug that shows broad-spectrum antiviral activity against several RNA viruses. This compound is currently under clinical development for the treatment of Ebola virus disease (EVD). While antiviral effects have been demon...
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| Publicado no: | Viruses |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520719/ https://ncbi.nlm.nih.gov/pubmed/30987343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11040326 |
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