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Recombinant RNA-Dependent RNA Polymerase Complex of Ebola Virus

Here we report on the expression, purification and characterization of recombinant ebola virus RNA-dependent RNA polymerase (EBOV RdRp). Active protein complexes composed of the large L protein and viral protein VP35 were isolated from insect cells and analyzed using a short primer/template substrat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tchesnokov, Egor P., Raeisimakiani, Parisa, Ngure, Marianne, Marchant, David, Götte, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838098/
https://ncbi.nlm.nih.gov/pubmed/29507309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22328-3
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