Synthetic miR-143 Exhibited an Anti-Cancer Effect via the Downregulation of K-RAS Networks of Renal Cell Cancer Cells In Vitro and In Vivo

To understand the role of RAS-signaling networks in the pathogenesis of renal cell carcisnoma, we clarified the relationship between miR-143 and RAS. The expression of miR-143 was extremely downregulated in tumor tissues from renal cell carcinoma patients compared with that in the adjacent normal ti...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Takai, Tomoaki, Tsujino, Takuya, Yoshikawa, Yuki, Inamoto, Teruo, Sugito, Nobuhiko, Kuranaga, Yuki, Heishima, Kazuki, Soga, Tomoyoshi, Hayashi, Kotaro, Miyata, Kanjiro, Kataoka, Kazunori, Azuma, Haruhito, Akao, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520334/
https://ncbi.nlm.nih.gov/pubmed/30930112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.03.004
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