A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells

Bladder cancer is one of the most difficult malignancies to control. We explored the use of a novel RNA-interference method for a driver oncogene regulating cancer specific energy metabolism by the combination treatment with a small interfering RNA (siRNA) and a microRNA. After transfection of T24 a...

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Publicado no:Int J Mol Sci
Main Authors: Takai, Tomoaki, Yoshikawa, Yuki, Inamoto, Teruo, Minami, Koichiro, Taniguchi, Kohei, Sugito, Nobuhiko, Kuranaga, Yuki, Shinohara, Haruka, Kumazaki, Minami, Tsujino, Takuya, Takahara, Kiyoshi, Ito, Yuko, Akao, Yukihiro, Azuma, Haruhito
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297811/
https://ncbi.nlm.nih.gov/pubmed/28106737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010179
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