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MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells

The Warburg effect is a well-known feature in cancer-specific metabolism. We previously reported on the role of microRNA (miR)-145 as a tumor-suppressor in human bladder cancer (BC) cells. In this study, we reveal that miR-145 decreases the Warburg effect by silencing KLF4 in BC cells. The expressio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Minami, Koichiro, Taniguchi, Kohei, Sugito, Nobuhiko, Kuranaga, Yuki, Inamoto, Teruo, Takahara, Kiyoshi, Takai, Tomoaki, Yoshikawa, Yuki, Kiyama, Satoshi, Akao, Yukihiro, Azuma, Haruhito
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464850/
https://ncbi.nlm.nih.gov/pubmed/28380435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16524
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